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Magento Store Locator Extension by FME



Magento store locator extension by FME increases your business by helping your customers find you, or your products, with the dealer locator. Store Locator lets you easily manage multi-location businesses online so your customers can find you anywhere.

This Google Map store locator Magento extension creates a dedicated store finder page fully integrated with Google Maps and allows your customers to get the shortest path towards the nearest store using the “Get Direction” button. You can drop the pins to customize the physical store exact location.

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System and Apparatus for Multimodality-compatible High-quality Intravital Radionuclide Imaging

Medicilon is a Preclinical Research Outsourcing (CRO) company. With our more than 10 years experience on preclinical research services, we dedicated to provide our clients with customized preclinical services program in drug metabolism, pharmacokinetics, efficacy studies, and toxicology. We provide our clients a high-quality data and rapid turnaround time to support their drug development, preclinical studies and clinical research and to help them to select the most valuable drug candidates into clinical trials stage. Email:[email protected] web:www.medicilon.com.
ABSTRACT:The present invention discloses an imaging system and apparatus to obtain high-resolution low-noise intravital radionuclide imaging based on transparent window chamber. This imaging system is dedicated to preclinical research. It comprises a transparent window chamber, in particular a dorsal skin window chamber or a cranial chamber or an ear chamber or a spine cord chamber on a living animal, and a high-quality radionuclide imaging camera for the imaging of positron or electron. The apparatus is compatible with multimodality imaging, in particular magnetic resonance imaging (MRI), microscopy imaging including fluorescence microscopy, phosphorescence microscopy and two-photon microscopy.
DESCRIPTION:The present invention discloses an imaging system and apparatus to obtain high-resolution low-noise intravital radionuclide imaging based on transparent window chamber. This imaging system is dedicated to preclinical research. It comprises a transparent window chamber, in particular a dorsal skin window chamber; cranial chamber, ear chamber or spine cord chamber on a living animal and a high-quality radionuclide imaging camera for the imaging of positron or electron. The apparatus is compatible with multimodality imaging, in particular magnetic resonance imaging (MRI), microscopy imaging including fluorescence microscopy, phosphorescence microscopy and two-photon microscopy.
The system of the present invention enables a reliable link between macroscopic imaging and microscopic physiological measurements. It allows high quality radionuclide imaging, high compatibility with multiple imaging modalities, precise co-registration of images obtained from different sources at different times and intact longitudinal multimodal observation. Thus the present invention can assist the validation and development of pharmaceutical, imaging, diagnostic and therapeutic techniques and strategies.
In contrast to conventional anatomical imaging such as CT or MRI, molecular imaging extends the clinical frontline to fundamental molecular pathways in organisms noninvasively, which supports the individualization of healthcare. Among all the molecular imaging modalities, radionuclide imaging such as positron emission tomography (PET) or single photon emission computed tomography (SPECT) are most widely used in clinical practice due to their high sensitivity of physiological differences and have shown enormous clinical value for example in early detection of cancer, staging, localization and therapy prognosis.
Radionuclide imaging is achieved through injection of radiolabeled molecular biomarkers, which generate contrast between normal and abnormal tissues according to their different metabolic properties of the injected biomarker. Various biomarkers have been developed for the detection of different physiological functions such as glycolysis (e.g. [18F]FDG, 99mTc-HMPAO), perfusion (e.g. [13N]Ammonia, 99mTc-tetrofosmin), hypoxia (e.g. [18F]Fmiso), proliferation (e.g. [18F]FLT) and so on.
The radioactive signals emitted from the radiolabeled biomarkers can be detected by radiation cameras (Scintigraphy), SPECT for single photon emitters or coincidence detectors (PET) for positron emitters.
After injection into the body, molecular biomarkers are delivered through macro- and microcirculatory system into tissues and then get either metabolized in the target area or cleared out. This complex procedure causes the acquired image to be influenced by many confounding factors, such as vascular delivery, interstitial transport and renal clearance. The interpretation of molecular imaging towards characteristics of the tumor microenvironment is therefore not straightforward.
For pharmaceutical development of new imaging biomarker or the application of clinical diagnosis and therapy planning, the assessment and validation of molecular imaging and its evaluation methods is necessary.
The assessment of molecular images requires a reliable link from macroscopic imaging to microscopic measurements. However, such a reliable link is not straightforward.
Conventionally, tumors need to be resected after animal scarification and be cut into sections for the investigation by microscopy. Although these in vitro methods have been widely used in various applications, they are destructive and have limited ability to provide insight into in vivo dynamics. The inconsistency between in vivo and in vitro does not meet the requirements for clinical applications such as biologically guided radiotherapy.
Furthermore, there exists a huge difference between typical preclinical and clinical molecular images (˜mm) and microscopic measurements (˜μm). The current preclinical PET can reach a resolution of approximately 1 mm while the preclinical SPECT can achieve 0.4 mm resolution for small animals. The measured signal in an imaging element is an integration of the signal over a relatively large scale of heterogeneous tumor microenvironment, which makes the validation of molecular imaging even more difficult.
The resolution of current radionuclide imaging devices is relatively low compared to morphological imaging modalities. For preclinical research of radionuclide imaging, high resolution is preferred.

Sebuah Panduan untuk mengunjungi Tirupati

Tirupati, «Uang Spiritual dari Andhra Pradesh» adalah benar-benar sebuah kota diakui sebagai salah satu tertentu di kota spiritual Hindu yang paling suci. Kota ini sebagian besar terkenal karena candi terutama untuk Tirumala Venkateswara Temple, salah satu tertentu dari kuil terkaya di India. Tiru berarti Dewi Lakshmi dan Pathi menunjukkan Partner. Jadi, sebenarnya diidentifikasi mengingat bahwa tempat tinggal Suci Wisnu.

 

Candi Tirumala Venkateswara dianggap sebagai salah satu tertentu dari delapan Swayambhu Kshetras dari tuan Wisnu. Arsitektur candi ini luar biasa, itu adalah mata penangkapan. Enviornment dari Garbhagriha ini sangat menenangkan. Meskipun setiap hari secara luas dikenal sebagai festival, Sri Venkateswara Brahmotsavams, sembilan hari kontes tahunan yang dirayakan setiap tahun sepanjang tiga puluh hari periode dari Oktober tonsuring rambut adalah sering berlaku di sana. Apabila anda ingin berwisata ke kota Pacitan dan menginginkan paket dan informasi tentang hotelnya, di sini terdapat paket dan informasi hotelnya, untuk harga hotel serta informasinya dapat di lihat di sini paket tour pacitan. paket dan informasi harga hotel ini akan memberikan petunjuk saat anda akan berwisata ke kota Pacitan. paket dan informasi ini juga di lengkapi dengan daftar hotel-hotel serta akomodasinya yang terjangkau, sehingga memberikan kenyamanan saat anda akan berwisata ke kota Pacitan.

 

Berbagai lainnya kuil terkenal adalah sebagai mengikuti:

• Venkateswara Temple Sri

• Govindarajaswami Kuil Sri

• Srikalahasti

• Kanipakam

Terlepas dari, ada berbagai daerah wisata lainnya: — • Pushkarini Tank

• Akash ganga air terjun

• Vari Museum Sri

• Deer Park

• TTD Gardens

• Talakona waterfal

Cara terbaik untuk mencapai:

Tirupati terletak di panjang dari ratus empat puluh lima km dari Chennai dan 416 km selatan-barat dari Banglore. Sementara, Tirupati adalah sekitar 55 3kms absen dari Hydrabad.

Lewat udara:

Renigunta mungkin yang paling dekat bandara ke Tirupati yang, sekitar 15 km. di kota. Penerbangan ke Renigunta Bandara dapat ditemukan dari, Chennai, Delhi, Bangalore, Hyderabad dan juga kota-kota penting lainnya. Sebuah single bisa mendapatkan Renigunta Bandara via taksi di harga yang adil.

By Rail:

stasiun kereta api Tirupati menghubungkan dengan Bangalore, Mumbai, Puri, Trivandrum, Chennai dan Hyderabad.

Dengan jalan raya:

Seseorang bisa mendapatkan Tirupati dengan menggunakan jalan. solusi yang ditawarkan adalah taksi dan bus. Sebuah single juga dapat memilih untuk tur tawaran kuil Tirupati dari Chennai, Hydrabad, Banglore.

Greatest waktu yang tepat untuk melihat pada:

Tirupati berkokok oleh umat semua sepanjang tahun. Oleh karena itu Anda tidak bisa lepas dari itu. Meski begitu, jika Anda mencari untuk kondisi iklim yang cocok untuk mengunjungi tempat Anda perlu pergi ke sana antara November dan Maret. Ingin berlibur ke kota Jogjakarta, dan menginginkan paket dan informasi tentang hotelnya, di sini terdapat paket dan informasi hotelnya, untuk harga hotel serta informasinya dapat di lihat di sini Pakej Bercuti Murah Ke Jogjakarta.

Penginapan:

Ada banyak menjadi solusi diakses. Sebuah single bisa pergi dengan pondok, sesuai dengan anggaran belanja, juga sebagai pondok-pondok, rumah tamu, dan kamar disewakan juga tersedia di sekitar candi Tirupati.

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Share some HPE Sales Certified HPE2-E65 exam questions and answers below.
How does the trend of customers moving to cloud solutions increase your sales opportunities?
A. You can batter focus on selling customers traditional infrastructure in the areas unaffected by cloud, compute and storage.
B. You can offer a promotion in which you buy back customers’ infrastructure in return for a discount on PHE public cloud services.
C. You can warn customers of the dangers of implementing cloud services, winning a role as a trusted advisor.
D. You can offer a hybrid solution that keeps some workloads on-premise, based on the customers’ unique needs.
Answer: D

Which customer presents the most immediate opportunity for HPE Network Protector SON Application?
A. A mid-sized company that experienced a security breach because an employee's account Was compromised
B. A small company that that is looking for new malware-detection software
C. A mid-sized company wants a solution that detects rogue Access Points (APS)
D. A large customer that wants to Implement stronger access controls
Answer: A

For which type of company should you suggest HPE Moonshoot?
A. Companies that are highly focused on big data
B. Companies that need a server that is optimized tor specialized workloads such as media processing.
C. Small businesses that want a bundled Converged System solution
D. Companies that need servers which are designed for virtualization density
Answer: D

Which qualifying question could you ask to validate the opportunity for selling HPE OneView?
A. Have you considered a server solution that can be integrated as a snap-in to the HP networking management tool Intelligent Management Center (IMC)?
B. Does your company need an industry-standard solution that validates wireless and wired user login requests?
C. Do you need a comprehensive Bring Your Own Device (BYOD) solution that enable selfregistration for guest users?
D. Have you considered a converged solution that spans servers, storage, and network and both physical virtual resources?
Answer: D

What type of stronge architecture do customers need in order to sport a private cloud or a hybrid cloud solution?
A. One that is flexible for different uses
B. On that is embedded with proprietary cloud management technologies.
C. On that is controlled by a dedicated storage management interface.
D. One that is defined by the underlying hardware.
Answer: D

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Preclinical time of flight imaging

Medicilon is a Preclinical Research Outsourcing (CRO) company. With our more than 10 years experience on preclinical research services, we dedicated to provide our clients with customized preclinical services program in drug metabolism, pharmacokinetics, efficacy studies, and toxicology. We provide our clients a high-quality data and rapid turnaround time to support their drug development, preclinical studies and clinical research and to help them to select the most valuable drug candidates into clinical trials stage. Email:[email protected] web:www.medicilon.com.
ABSTRACT:A preclinical positron emission tomography (PET) imaging method includes acquiring time-of-flight localized PET imaging data from one or more non-human animal subjects and reconstructing the acquired data to form an image. In an illustrative PET scanner includes: radiation detectors (12) viewing an examination region; a subject support assembly (14) supporting a plurality of preclinical studies subjects in the examination region for simultaneous PET imaging; coincidence electronics (20) acquiring time-of-flight localized PET imaging data from the preclinical subjects using the radiation detectors; and reconstruction electronics (22) that (i) perform a filtering operation based at least in part on the time-of flight information, the filtering operation including at least one of discarding non-probative time-of-flight localized PET imaging data and associating time-of-flight localized PET imaging data with individual preclinical subjects and (ii) reconstruct the filtered data to form images of the preclinical subjects.
DESCRIPTION:This application claims the benefit of U.S. provisional application Ser. No. 60/974,585 filed Sep. 24, 2007, which is incorporated herein by reference.
The following relates to the medical arts, and more particularly to preclinical imaging using positron emission tomography (PET), and is described with particular reference thereto. However, the following will find further application in other tasks such as PET imaging for veterinary diagnosis.
In conventional PET imaging, a radiopharmaceutical is administered to a subject so as to distribute through the subject or to aggregate in portions of the subject that are of interest, such as anatomical tissue of interest. The radiopharmaceutical exhibits positron-electron annihilation events that generate oppositely directed gamma rays each having energy of 511 keV. Radiation detectors arranged around the subject detect substantially simultaneous gamma ray detections, i.e. within a selected coincidence time window, and the substantially simultaneous gamma ray detections are assumed to be sourced by the same positron-electron annihilation event lying at some point along the line-of-response connecting the two substantially simultaneous or coincident gamma ray detection events. A data set of such lines-of-response is generated, and is reconstructed using filtered backprojection, iterative backprojection, or another technique to obtain an image of the radiopharmaceutical distribution in the subject.
Time of flight PET imaging is similar, but makes use of the finite time difference between the substantially coincident gamma ray detection events to localize the positron-electron annihilation event along the line-of-response. A gamma ray travels at the speed of light ©, i.e. about 3 centimeters every 100 picoseconds. The spatial localization (Δx) is given by Δx˜c•Δt/2, so for a radiation detector having, as a typical example, a temporal resolution of about 600 picoseconds it follows that the time-of-flight localization provides a spatial resolution along the line-of-response of about 9 centimeters. In practice, this localization may be represented, for example, by a Gaussian distribution having a FWHM of about 9 centimeters. Spatial localization on the order of Δx=9 centimeters is advantageous for imaging a typical human subject having a size substantially larger than this spatial localization.
On the other hand, a mouse, rat, guinea pig, or other small animal of the type typically used in preclinical research is of a size smaller than or comparable with the spatial localization Δx provided by time-of-flight information. Accordingly, time-of-flight localization does not provide additional useful information as to the location of the positron-electron annihilation event within the animal. This recognition, coupled with the substantial additional expense of including high-speed radiation detectors and high-speed and high-capacity time-of-flight localization processing, has heretofore motivated against including time-of-flight capability in preclinical PET scanners.
Moreover, existing preclinical studies have typically used preclinical PET imaging to assess large-scale anatomical features of tumors or other large-scale growths resulting from cancer or other pathologies under study. For example, a study may quantify the effect of a therapy by the reduction in average tumor size (if any) in a statistically significant number of test animals. Such assessments are readily performed using PET imaging since the tumors of interest are substantially larger than the spatial resolution of a typical PET scanner. If the therapy successfully reduces the tumor size below the resolution of the conventional preclinical PET scanner, it is generally assumed that the therapy is indeed effective. This approach is convenient and provides readily comprehended metrics such as tumor size. However, the measured large-scale anatomical features may, or may not, be probative of outcome determinating aspects of the cancer such as the extent of metastasis, that is, the extent to which cancerous tissue has spread away from the primary tumor. It is known that most cancer patients succumb to the effects of metastatic cancer.
The following provides new and improved apparatuses and methods which overcome the above-referenced problems and others.